Effect of metabolic therapy on the state of the vascular bed in premenopausal dyslipidemia

Abstract

When scanning the common carotid arteries (CCA), it was found that patients with premenopausal arterial hypertension (AH) with dyslipidemia with reduced estradiol levels had an expansion of the CCA lumen, a decrease in the blood flow rate in the carotid arteries without hemodynamically significant stenoses, which may indicate the development of vascular maladaptation due to a violation of the autoregulation mechanism, due to remodeling of the vascular wall caused by hypoestrogenemia, and indicate more pronounced structural and functional changes in the vessel in the form of arteriosclerosis, increased stiffness of the vascular wall and the development of endothelial dysfunction. Combined therapy with an angiotensin-converting enzyme (ACE) inhibitor and BioDihydroquercetin has a positive effect on structural and functional changes in the vascular wall of the CCA, endothelial dysfunction improves lipid spectrum parameters, reduces the stiffness of the vascular wall of the arteries. The drug BioDihydroquercetin, produced with trade mark “Baikal Legend”, is a natural immunomodulator, antioxidant, capillaroprotector, strengthens blood vessels, improves blood microcirculation, it is recommended to slow down the aging process of the body