Abstract

The effect of metabolic syndrome on patients with pre-diabetes in regard to cardiovascular and cerebrovascular diseases (CCVD) was investigated.The subjets with pre-diabetes were divided into metabolic syndrome (MS) group and non-MS.Follow-up after the baseline survey,the new-onset cardiovascular events of patients were collected.The incidence of CCVD in the MS group was 5.66%,being higher than 1.88% in non-MS group (P<0.05).After factors being corrected,compared with the non-MS group,the relative risk (RR) of CCVD in MS group was 2.616 (95% CI 1.328-5.153).Compared to only 1 component of MS patients,the risks of CCVD in MS component 2,≥3 patients were increased by 29% (HR =1.29) and 62% (HR =1.62).Metabolic syndrome may increase the risk of cardiovascular and cerebrovascular diseases in pre-diabetes populations.The occurrence of CCVD and MS content showed a dose-dependent relationship. Key words: Metabolic syndrome; Diabetes; Cardiovascular

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