Effect of Memorial Sloan-Kettering Cancer Center (MSKCC) nomogram to avoid conventional axillary dissection of one node–metastasis Japanese patients with breast cancer.

Abstract

e11531 Background: Our aim was to define the role of MSKCC nomogram in avoiding conventional axillary dissection of one node-metastasis breast cancer patients. Methods: Between January 2009 to November 2010, clinically axillary node negative consecutive 186 patients underwent sentinel lymph node biopsy using 12 mg Indigo carmine in our institution. Results: In 14 (7.5%) of the 186 cases with metastatic axillary nodes were node positive and underwent axillary dissection. Final pathological results shows 10 of 14 patients revealed one node-metastasis and four patients revealed more than 2 node-metastasis. Assessment of MSKCC nomogram, average of probability of spread to additional lymph node were 25.4% for the former group, 54% for the latter group. Conclusions: Our study confirms MSKCC nomogram’s role in sentinel lymph node biopsy of breast cancer surgery. MSKCC nomogram may prove useful in avoiding benefit from axillary dissection of only one node-metastasis breast cancer patients.