Effect of medication adherence therapy on the quality of life of patients with primary depression

Abstract

Objective To explore the effect of medication adherence therapy on the survival status of patients with primary depression. Methods From July 2011 to December 2013, 55 cases of depression patients in our hospital were treated as control group, and routine health education was implemented. From January 2014 to June 2016 in our hospital and the 57 first treatment of depression patients choosing for observation group, received the routine care and the implementation of medication adherence for the treatment method of education. The scores were assessed in SDS score at 3 months and 6 months after admission, the quality of life score at admission and 6 months after intervention, and the compliance of treatment at 6 months after the intervention. Results At the time of admission of two groups patients with depression score difference was not statistically significant (t=1.124, P=0.059) ; after interventions for 3 months and 6 months in the observation group, the patients with depression scores were significantly lower than that of the control group, and the difference was statistically significant (t=3.986, 8.532; P<0.01) . The implementation of drug compliance therapy intervention, observation group of patients in the medication compliance, timely review, reasonable rest, reasonable diet, reasonable exercise, prevention of infection, smoking and drinking in 7 dimensions and total score were significantly higher than those of the control group, and there was significant difference between two groups (t= 6.022, 6.954, 5.863, 5.042, 6.514, 5.652, 4.675, 5.868; P<0.01) . Patients in the observation group in physiological function, psychological function, social function, health self cognition and total quality of life scores improved significantly higher than that in the control group, and the differences were statistically significant (t=5.265, 4.638, 4.267, 4.146, 3.955; P<0.01) . Conclusions Medication adherence therapy can improve the treatment compliance of patients, reduce the degree of depression, and improve the quality of life of patients. Key words: Depressive disorder; Drug compliance; Quality of life