Abstract
Abstract Mebendazole given per os was found to be effective against larval Echinococcus granulosus infection in pigs. Twenty-four pigs were experimentally inoculated with adult E. granulosus tapeworms. Mebendazole (40 mg/kg) or placebo was injected into six pigs 2 months after infection. Seven other pigs were given mebendazole (25 mg/kg) in their feed for 10 days twice (2 and 5 months after infection). Post-mortem examination performed 8 months after infection revealed that two of the pigs treated with mebendazole per os had a single hydatid cyst each; the other five pigs were free of infection. All eleven control untreated pigs were infected with between two and 21 cysts of E. granulosus . Mebendazole given intraperitoneally was not effective as mebendazole given per os in preventing the development of hydatid cysts in pigs.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have