Abstract
Background and Objectives The fetal period is an important stage in a person’s life. Exercise during pregnancy has been considered as a positive factor in preventing chronic diseases in adulthood. The aim of this study was to investigate the role of maternal high intensity exercise before and during pregnancy on serum levels of lipid profile of adult offspring. Subjects and Methods Twenty-four rats (170-200g) were divided into three maternal groups: Control (C), exercise Before Pregnancy (BP) and exercise before and during pregnancy (BDP). Exercise performed before pregnancy for six weeks and during pregnancy for three weeks; one minute with 80% -95% vo2max switching with two minutes of active recovery (65% vo2max) for five days/week. After end of the training birth process and breastfeeding, the offspring were divided according to theirs’s mother group and they were kept until adult age. The serum levels of LDL, HDL, TG and Cho were measured by enzymic method. Results The one-way ANOVA result showed that maternal exercise before and during pregnancy significantly reduced LDL, Cho and LDL/HDL cholesterol ratio in male (P=0.03, P=0.2, P=0.04) and female (P=0.00, P=0.02, P=0.04) offspring. Conclusion This finding suggests that maternal high-intensity-interval training as an appropriate environmental intervention can help to improve the health of the next generation.
Highlights
The aim of this study was to investigate the role of maternal high intensity exercise before and during pregnancy on serum levels of lipid profile of adult offspring
Exercise performed before pregnancy for six weeks and during pregnancy for three weeks; one minute with 80% -95% vo2max switching with two minutes of active recovery (65% vo2max) for five days/week
The one-way ANOVA result showed that maternal exercise before and during pregnancy significantly reduced LDL, Cho and LDL/HDL cholesterol ratio in male (P=0.03, P=0.2, P=0.04) and female (P=0.00, P=0.02, P=0.04) offspring
Summary
Background and ObjectivesThe fetal period is an important stage in a person’s life. Exercise during pregnancy has been considered as a positive factor in preventing chronic diseases in adulthood. The aim of this study was to investigate the role of maternal high intensity exercise before and during pregnancy on serum levels of lipid profile of adult offspring. Subjects and Methods Twenty-four rats (170-200g) were divided into three maternal groups: Control (C), exercise Before Pregnancy (BP) and exercise before and during pregnancy (BDP). After end of the training birth process and breastfeeding, the offspring were divided according to theirs’s mother group and they were kept until adult age. The serum levels of LDL, HDL, TG and Cho were measured by enzymic method. Results The one-way ANOVA result showed that maternal exercise before and during pregnancy significantly reduced LDL, Cho and LDL/HDL cholesterol ratio in male (P=0.03, P=0.2, P=0.04) and female (P=0.00, P=0.02, P=0.04) offspring
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