Abstract

L-malate is an important intermediate on the process of metabolism; it plays an important role in generating mitochondria ATP both under aerobic and hypoxic condition. It is easy to be absorbed and come into mitochondrion through cell membrane and promote to produce energy in mitochondrion. The purpose of this investigation is to probe into the different influence malate ingestion on blood lactate and glucose kinetics during aerobic exercise athletes; at the same time, rats were used to study the effect of malate and oligosaccharide solution on the metabolism in muscle and liver. The supplement of malate-oligosaccharide solution may improve the level of antioxidants in vivo after exercise, and subsequently increase the total antioxidant capacity and decrease the level of lipid peroxidation. At the appropriate time sports drinks can add varying degrees of motion to extend time to fatigue enhance athletic ability, speed up the recovery process after exercise, reduce fatigue.

Highlights

  • L-malate, an important organic acid in the process of metabolism, plays an important role in generating mitochondria ATP

  • The result shows that cyclist supplied with malate plus oligosaccharide solution performed the cycling to exhaustion for a longer time Malate plus oligosaccharide solution has good effect on maintaining a higher blood glucose concentration during exercise, increase blood lactate removal rate, decreases the level of serum GOT and GPT after exercise, postpone the occur of fatigue

  • L-malic acid is an important organic acids produced during the metabolism of organisms, is the citric acid cycle (TCA cycle) and its branch glyoxysome metabolic processes important intermediate product, the intermediate product is CO2 fixation reactions

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Summary

INTRODUCTION

L-malate, an important organic acid in the process of metabolism, plays an important role in generating mitochondria ATP. L-malic acid is an important organic acids produced during the metabolism of organisms, is the citric acid cycle (TCA cycle) and its branch glyoxysome metabolic processes important intermediate product, the intermediate product is CO2 fixation reactions It is the living cell exists in an active substance, absorbed, can quickly through the cell membrane into the important part of the direct involvement of the inner mitochondrial malic acid is malic acid aspartate shuttle, for cytosolic (cytosol) and reducing equivalents mitochondria (mitochondria) between (NADH) play an important role in metastasis. Important organic acids malic acid produced as human metabolic processes, is an intermediate metabolite of the citric acid cycle, directly involved in mitochondrial energy metabolism; but it is malate - aspartate shuttle part, to between cytosolic and mitochondrial transfer reducing equivalents play an important regulatory role

ANTIOXIDANTS OUTLINE ITS MECHANISM
Several important antioxidant substances
THE ANTIOXIDANT THAT MALIC ACID MIGHT HAVE
PHYSIOLOGICAL ROLE OF MALIC ACID
CONCLUSION
Full Text
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