Abstract
The objective was to determine the bile acid binding capacity of Maillard reaction products (MRPs) and its effect on plasma cholesterol (chol) and gastrointestinal weight in rats. MRP was prepared by heating a mixture of 3 M α-D-glucose and 3 M L-lysine at pH 9.0 and washing with ethanol to reduce low molecular weight MRP. In vitro data indicated that high molecular weight MRP bound cholic and chenodeoxycholic acid. Purified diets were prepared with 5% cellulose (C), 2.5% MRP plus 2.5% cellulose (CM), or 5% MRP (M) and fed to three groups of male Wistar rats (n=10) for 4 weeks
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