Abstract
The effect of thoracic duct lymph drainage on portal pressure and bleeding esophageal varices in 7 patients with cirrhosis has been evaluated. Four control patients with cirrhosis and bleeding varices were monitored in similar fashion without lymph drainage. Significant reductions in portal pressure were associated with hypovolemia from inadequate lymph replacement or recurrent hemorrhage from esophageal varices. The portal, central venous, and arterial pressures, urine output, and body weight remain unchanged when lymph was reinfused at the same rate as withdrawal. The functional thoracic duct pressure approached the central venous pressure. lymph drainage did not appear to control hemorrhage from varices since bleeding continued or recurred in 4 patients while lymph was being drained.
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