Abstract
Introduction:Low-level laser therapy (LLLT) is effective in preventing fatigue and in stimulating the microcirculation and cellular activity. In this study, we examined the effect of LLLT on injured tibial muscle in vivo by assessing muscle function during fatigue.MethodsTwenty-four male mice were used. Each mouse received an injection of sterile 0.9% saline solution (50 µL) in the right tibialis anterior muscle, after which the tendon of the muscle was exposed, connected to an isometric transducer and subjected to a resting tension of 1 g. A bipolar electrode was attached to the tibial nerve for electrical stimulation. The mice were randomly allocated to one of two groups: G1 (control: 3 h – n=8 and 9 h – n=5) and G2 (treated with GaAlAs laser, λ660 nm, 35 mW, 0.6 J, 17 s: 3 h – n=6 and 9 h – n=5).ResultsIn G1 mice, the amplitude of the tetanic contracture in response to induced fatigue remained unchanged during six consecutive tetani. The amplitude of the tetanic contractions in response to electrical stimulation (4-8 mV) was also unchanged. These results indicated muscle intactness in response to the load imposed by tetanus. In G2 mice, there was an increase in the amplitude of contraction after 3 h and 9 h when compared to G1 at 83% tetanus.ConclusionThese results indicate that exposure of muscle to LLLT enhanced the contractile force and increased the resistance to muscle fatigue without causing morphological damage to cellular structures.
Highlights
Low-level laser therapy (LLLT) is effective in preventing fatigue and in stimulating the microcirculation and cellular activity
Most studies of the effects of low-level laser therapy (LLLT) in laboratory animals have been done in rats and have shown that LLLT can reduce the weakness of local fatigue on muscle force and possibly reduce muscle damage after strenuous exercises (AlbuquerquePontes et al, 2015; Caetano and Zanuto et al, 2013; Lopes-Martins et al, 2006; Santos et al, 2014)
Little is known of the responses to LLLT in other species, various reports have demonstrated the benefits of LLLT in improving muscle function in dystrophic mice (Leal‐Junior et al, 2014; Oron et al, 2014; Silva et al, 2015)
Summary
Low-level laser therapy (LLLT) is effective in preventing fatigue and in stimulating the microcirculation and cellular activity. Experimental studies have shown that laser therapy can attenuate the local damage caused by snake venoms, as assessed histologically and based on the quantification of marker proteins or enzymes (Barbosa et al, 2008; 2009; Doin-Silva et al, 2009; Dourado et al, 2003; Nadur-Andrade et al, 2012; 2014).
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
