Abstract

The effect of a static electric field on the production of urokinase (UK) by AUB 101 cell line obtained from a kidney biopsy tissue of a mesangio proliferative glomerulo nephritic patient was studied. Cells were exposed to varying field intensities viz. 2.5–20 V and assayed for UK activity by a fibrin plate method. A gradual increase in UK activity was observed with increase in field strengths up to 10 V A. A maxima increase in UK production was observed in cells exposed to a electric field intensity of 10 V which amounts to 66% enhancement.

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