Abstract
Previous results have shown that low dose rate ionizing radiation shortens the life span of fibroblasts with a limited growth potential (chicken fibroblasts). In the present work the same type of irradiation was done on mouse fibroblasts which invariably acquire an unlimited growth potential in vitro. It was found that contrary to the results obtained with chicken cells, irradiation accelerated the establishment of mouse fibroblasts. The results suggest that low dose rate ionizing radiation accelerates a natural phenomenon in each cell type tested and are additional proof that the life span in vitro of fibroblast populations is a property that depends on the cell rather than on the environment.
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