Abstract
After long-term antihypertensive treatment (mean 25 months, range 18–38 months), the cerebral blood flow (CBF) in both symptomatic and asymptomatic hemispheres remained unchanged despite a reduction in blood pressure in 24 hypertensive cases with chronic cerebral infarction. However, there was a positive correlation between the change in systolic or mean blood pressure and the change in CBF in the symptomatic hemisphere (p < 0.05). Our data suggest that more than 80% of the pretreatment level of blood pressure or 120 mm Hg of systolic blood pressure might be a preferable lower level of blood pressure for antihypertensive treatment in patients with chronic cerebral infarction.
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