Abstract
A single injection (200 mg/kg, intraperitoneally) or a course of injections (100 mg/kg subcutaneously, daily for 10 days) of lithium chloride given to rats had no significant effect on the content of catecholamines and dihydroxyphenylalanine in the brain stem 1, and 4 h after the injections. In experiments on rabbits the compound (100 mg/kg, intravenously) increased the noradrenalin concentration in the thalamus, hypothalamus, reticular formation, and caudate nucleus. An increase in the dopamine content in the caudate nucleus was accompanied by a simultaneous decrease in its concentration in the thalamus, hypothalamus, reticular formation, amygdala, and hippocampus.
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