Abstract
Lidocaine injected into suckling rabbits infected with a virulent strain ofVibrio cholerae abolishes the development of hydropic and ballooning degeneration the jejunal enterocytes. Secretory granules and lipid inclusions accumulate in jejunal enterochromaffin cells and interstitial cells of renal medulla, respectively, and are not released into the vascular bed. In pulmonary tissue ultrastructural changes are mild, and capillary epithelium is undamaged, indicating that lidocaine stimulates pulmonary enzymes which inactivate biologically active substances implicated in the pathogenesis of cholera.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.