Abstract
A peptic ulcer is sore on the lining of the stomach or duodenum; the two most common types of peptic ulcer are celled gastric ulcer and duodenum ulcer. Peptic ulcer are found to be due to an imbalance between aggressive factor such as hydrochloric acid (HCL), pepsin and refluxed bile. As the current study aimed to investigate the protective effect of Licorice against peptic ulcer.Thirty male Wistar albino rats were randomly divided into five groups (n = 6) as follow; -ve control group fed basal diet, +ve control group fed basal diet and injected with a single dose of Ranitidine (20mg/kg/day, bw, p.o.) (7 days). Groups 3-5 fed licorice with 1 ml. once a week, 1 ml. twice a week, 1 ml. three times a week respectively. Results revealed that licorice caused a significant decrease in blood cholesterol level, TG, LDL, AST, ALT, urea nitrogen, uric acid, creatinine, uric acid, albumin and VLDL. In addition, licorice caused a significant increase in HDL and PH, especially in group 5 which fed 3 ml. compared to +ve control group.
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