Abstract
The objective of this article is to review the in vivo and in vitro effects of using levonorgestrel (LNG) as emergency contraception (EC) on sperm function. Seven articles and an abstract containing data on the effects of using LNG as EC on sperm function were reviewed. Except for two early studies, in vitro and in vivo studies showed no significant effect of using LNG as EC on the number of spermatozoa penetrating the cervical mucus and reaching the uterine cavity, the number of spermatozoa adhering to the Fallopian isthmus or ampulla, or the number of spermatozoa adhering to the human tubal epithelium. Furthermore, no effect was found on sperm–zona pellucida binding capacity or the percentage of spermatozoa with D-mannose receptors when testing physiological doses of LNG. The only significant effect was a dose-dependent impairment of sperm motility. In conclusion, as EC, LNG does not apparently affect sperm function in vitro or in vivo. However, further studies should be conducted in order to evaluate t...
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
