Abstract
ANEMIA IN DOGS CAN BE PRODUCED by the administration of large doses of estrogens, such as estradiol benzoate, estrone (I–6)2 and diethylstilbestrol (7, 8)2 that is by substances ofvaried constitution whose common character-istic is estrogenic activity. Anemia can be produced in both sexes by this means. On the other hand androgenic substances such as testosterone or its propionate do not produce an anemia even after injection for a period of months (6). Healthy, vigorous dogs were used for the experiments. They were kept on a mixed diet which contained all the known vitamins. Before the investigation was commenced they lived for at least one week in their new surroundings. Blood was taken from the ear of fasting dogs and was analyzed immediately without the addi-tion of anticoagulants. Hemoglobin was measured by Sahli's method and the number of blood corpuscles determined in the Thoma-Zeiss chamber.
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