Abstract
Background: In obese subjects with type 2 diabetes mellitus (T2DM), the effect of laparoscopic greater curvature plication (LGCP) on the clinical improvement of T2DM is unknown. This study aims to investigate the effect of LGCP in improving the clinical profile of patients with T2DM. Materials and Methods: This is a retrospective study of obese subjects with T2DM who underwent LGCP between March 2011 and March 2013. Patients were followed up at different time periods. The efficacy of the procedure was investigated by using chi and t tests. Univariate and multivariate analyses were performed to investigate the predictors of excess weight loss (EWL). Results: Forty-three obese subjects (25 females, 18 males) with T2DM were enrolled. Mean age was 41.6 years. Preoperative mean ± SEM body–mass index (BMI) was 44.4 ± 0.8 kg/m2. Mean BMI decreased significantly at 1, 3, 6, and 12 months (p = 0.0002, p < 0.001, p < 0.001, and p < 0.001). Mean EWL was 20%, 32%, 42%, and 48% at 1, 3, 6, and 12 months of follow-up. ...
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