Effect of KRAS Mutational Status on Surgical Outcomes for Colorectal Liver Metastases: Results from the Colorectal Liver Operative Metastasis International Collaborative

J. Stauffer,O. Moaven,C. Mangieri,E. Levine,A. Wisneski,K. Perry,R. Gawdi,G. Russell,C. Clark,T. Cheung,C. Corvera,C. Valenzuela,P. Shen,C. Cha,N. Del Piccolo

doi:10.1016/j.hpb.2022.05.171

Effect of KRAS Mutational Status on Surgical Outcomes for Colorectal Liver Metastases: Results from the Colorectal Liver Operative Metastasis International Collaborative

J. Stauffer, O. Moaven + Show 13 more

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https://doi.org/10.1016/j.hpb.2022.05.171

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Journal: HPB	Publication Date: Jan 1, 2022
License type: elsevier-specific: oa user license

Affiliation: Jacksonville College, Mayo Clinic, Atrium Health Wake Forest Baptist, University of California, San Francisco, Chinese University of Hong Kong, University of Hong Kong, Yale University

#Surgical Treatment Of Colorectal Liver Metastases #Treatment For Colorectal Liver Metastases + Show 8 more

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Abstract

Introduction: Laterality of colorectal cancers appears to affect outcomes after surgical treatment for Colorectal Liver Metastases (CLM). KRAS mutations are thought to play a role. We hypothesized a differential effect of primary tumor laterality on long-term outcomes after surgical treatment of CLM, and that KRAS mutations influence this effect.

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