Abstract

Purpose: Diets which have influence on wellness could alter in their structure. Apart from weight control, different diets are used in the treatment of many diseases. Ketogenic diet(KD) has been ventured to remedy of neurological diseases and obesity. Multiple sclerosis(MS) is a complex progressive disease of the central nervous system and it has an influence on quality of voice. Voice Handicap Index (VHI) is an assay that presents data to clinical and physiological appraisal about voice. We measured the effect of KD and RD on voice quality(VQ). Methods: Sixty-eight subjects with MS who narrated a voice disorder associated to their disease were indiscriminately distributed to the KD or regula diet(RD) groups. We studied the VHI alter of patients before and 3 months after diet. Results: Sixty-five MS subjects accomplished the study. Baseline VHI rates did not diverge seriously between groups. In the KD group, statistically improvement was seen in all VHI parameters 3 months after diet (p˂ 0.001). Conclusion: Presently there are many therapies that aim speech and voice disorders in patients with MS. As such KD may be an option therapy to renovate VQ of patients with MS. A bigger sample size is required to find the function and pathophysiology of KD on VQ of MS patients.

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