Abstract
Metabolic syndrome is a cluster of disorders diagnosed simultaneously in an individual. The percentage of individuals affected from this syndrome is escalating around the globe as well as in Pakistan mainly due to more consumption of energy dense foods and sedentary lifestyle. Dietary modification with nutrient dense foods is a globally adapted strategy to reduce the complexity of this issue. This present project has been designed to see the impact of nutrient dense walnuts consumption on selective biomarkers in human subjects. The screening of human subjects was done by taking the anthropometric measurements, lipid profile, blood glucose level and blood pressure whereas the dietary pattern of patients was collected by validated food frequency questionnaire. The proximate analysis of walnuts was also done. Twenty patients were selected and divided into two groups randomly. Experimental group consumed walnuts daily for 8 weeks and placebo group consumed the diet without walnut. Selective physical parameters included BMI was performed at the regular basis whereas, the blood samples were collected at 1st , 4th and 8th week of the study period followed by the evaluation of serum triglyceride and high density lipoprotein cholesterol level. Walnuts were found to be high in fat content i.e 64.6% and also contained all other important nutrients as moisture (3.9%), ash (1.5%), protein (15.3%), fiber (1.5%) and nitrogen free extract (10.7%). Walnuts reduced triglycerides significantly and HDL was also raised significantly. No significant change was observed in BMI. Statistical analysis was employed to draw the conclusive outcomes of the research studies.
Highlights
The current time has seen the escalation of computerization and mechanization, with better transport resultant in modifications in lifestyle from active to sedentary and making a huge influence on human health [1]
Over the last 2 decades, focus on the metabolic syndrome has progressively increased, and studies have revealed that the prevalence of metabolic syndrome is steadily increasing in all populations worldwide, identifying this as one of the main global public health challenges of current times [2].The high prevalence of metabolic syndrome and cardiovascular disease (CVD) risk factors have been reported in South Asians
The 5 major risk factors of metabolic syndrome; i.e. triglyceride level, high density lipoprotein cholesterol level, blood pressure, plasma glucose level and abdominal obesity was determined at the start of the study and 3 selected makers which include obesity, high density lipoprotein cholesterol and triglyceride level were chosen for further the study of 2 months
Summary
The current time has seen the escalation of computerization and mechanization, with better transport resultant in modifications in lifestyle from active to sedentary and making a huge influence on human health [1]. Walnut kernel is a rich source of proteins, fats, vitamins, minerals and polyphenols which makes the fruit indispensible for human nutrition. They are a good source of flavonoids, sterols, pectic substances, phenolic acids and related polyphenols. The 5 major risk factors of metabolic syndrome; i.e. triglyceride level, high density lipoprotein cholesterol level, blood pressure, plasma glucose level and abdominal obesity was determined at the start of the study and 3 selected makers which include obesity, high density lipoprotein cholesterol and triglyceride level were chosen for further the study of 2 months. To access the effect of continual consumption of two servings of walnuts 25 g in each per day on the selective risk factors of patients with metabolic syndrome, this amount of walnut was provided to patients and prescribed them recommended eating plan.
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