Abstract
Renal impairment (RI) is a common feature in multiple myeloma (MM) and an adverse predictor of survival. Anti-myeloma treatments that can also improve renal function in patients (pts) with MM are required. ICARIA-MM was a randomized, open-label, active-controlled, multicenter phase 3 study that investigated the anti-CD38 monoclonal antibody isatuximab (Isa) in combination with pomalidomide and dexamethasone (Pd) in pts with relapsed/refractory MM (RRMM) and ≥2 prior lines of therapy (NCT02990338).
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