Abstract
ObjectivesMany materials and surface preparations have been developed to resist the formation of biofilm. Ion-bombarded silicone tympanostomy tube was introduced to resist both staphylococcal and pseudomonal biofilm formation. To date, there are no reports that have evaluated the use of ion-bombarded tympanostomy tubes against the ciprofloxacin-resistant Pseudomonas aeruginosa (CRPA) biofilm formation. The purpose of this study is to evaluate the ion-bombarded tympanostomy tube for CRPA biofilm resistance. MethodsCommercial ion-bombarded tympanostomy tubes and simple silicone tympanostomy tubes were processed for an evaluation of the CRPA biofilm formation in vitro. ResultsThe ion-bombarded tubes showed no resistance to CRPA adhesion and biofilm formation. Thick and dense conglomeration was less formed in the ion-bombarded tympanostomy tubes, compared to that of the simple silicone tube. ConclusionThe preventive effect against the CRPA biofilm formation of the ion-bombarded silicone tympanostomy tube was not observed. Our result suggests that only the surface modification by an ion bombardment is not enough to resist CRPA biofilm formation.
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