Abstract
Background: The present study aims at comparing the efcacy of intravenous Esmolol to Intravenous Lignocaine in attenuation of hemodynamic stress response to endotracheal extubation in cases of elective surgery in adult patients. Methodology: 60 subjects were enrolled and by Simple Randomisation, patients were divided into two groups of 30 each, Group E and L Group E received iv. Esmolol 1.5mg/kg and Group L received iv. Lignocaine 1.5mg/kg. Hemodynamic responses were recorded. Results: The HR, SBP, DBP, MAP were signicantly reduced in Esmolol group than in Lignocaine group, p<0.05. Conclusion: This study concludes that Intrvenous esmolol 1.5mg/kg is more effective than Intrvenous Lignocaine 1.5mg/kg in blunting the hemodynamic stress response to extubation
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