Abstract

Because intravenous fat emulsions are now frequently employed as nutritional supplements and because a relationship between increased viscosity and thrombosis has been suggested, 1 it appeared important to determine whether these substances increase blood viscosity in human beings. Swank 2 has demonstrated marked changes in the viscosity of blood following intravenous administration of lipids to dogs and after ingestion of large quantities of fat by hamsters. 3 His studies were not extended to man. In order to assess the effect of injected fat emulsions on the viscosity of circulating blood, an in vivo technique of measuring viscosity 4 was utilized. Method The method of determining blood viscosity employed in the present study is based on Poiseuille's law that during laminar flow of a homogeneous fluid in a tube of constant diameter the frictional loss bears a linear relationship to the volumetric rate of flow and is independent of the vessel

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