Abstract

The present studies examined the effect of intraluminal PGE<sub>2</sub> and systemic indomethacin on sodium chloride transport in the superficial distal tubule of the rat nephron. Controlled quantities of sodium chloride delivery to this segment were provided by in vivo microperfusion techniques. Neither <i>2</i>µ<i>M </i>intraluminal PGE<sub>2</sub>, 2 mg/kg body weight indomethacin given intravenously nor the combination of these agents affected sodium chloride transport in this nephron segment.

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