Effect of Intralesional Steroid Injection in Bilateral Benign Vocal Fold Lesions

Abstract

Abstract Background Corticosteroids are one of the most potent inhibitors of inflammation and wound repair. Local injection of steroid gives the option of administration of a potent drug locally, thereby avoiding the systemic side effects of them. They have been used in the last decade in managing benign vocal fold lesions as intralesional steroid injection has the advantages of rapid subsidence of the inflammation and edema with rapid improvement of voice postoperatively Ailil of the work This study is designed to show clinical ancl encloscopic voice Iinprovelnent of microlaryngeal surgery alone versus microlaryngeal surgery of the prilnary lesion combined with steroid injection in the opposing lesion in patients with bilateral vocal fold benign lesions. Patients and methods 40 patients with bilateral benign vocal fold lesions with Inoclerate to severe dysphonia are divided into two groups, one group underwent microlaryngo-surgery with excision of the primary lesion and injection of steroids into the contralateral lesions. The second group underwent microlaryngo-surgery with excision of the primary lesion only. Each subject was evaluated, preoperatively and postoperatively through a protocol including auditory perceptual assessment, laryngoscopic picture and self-rating by the patient using VHI. Results Comparing pre and post therapy results for each group, there was statistically significant improvcmcnt (reduction) in the size of thc contralatcral lesion and significant improvement in the quality of voice quality resulting in overall improvement in VHI. Conclusion Intralesional steroid injection in the contralateral lesion in bilateral benign vocal fold lesions is effective in improving voice quality postoperatively