Abstract
Background and Aims:Intraabdominal hypertension (IAH) is poorly diagnosed condition that cause splanchnic hypoperfusion and abdominal organs ischemia and can lead to multiple organ failure. There are no scientific data regarding effect of intraabdominal pressure (IAP) on splanchnic circulation in children.Material and Methods:Ninety-four children after surgery for appendicular peritonitis were enrolled in the study. After IAP measurement children were included in one of two groups according IAP levels: βwithout IAHβ (n = 51) and βwith IAHβ (n = 43). Superior mesenteric artery (SMA) and portal vein (PV) blood flows (BFSMA, BFPV, mL/min) were measured, and SMA and PV blood flow indexes (BFISMA, BFIPV, ml/min*m2) and abdominal perfusion pressure (APP) were calculated in both groups.Results:Median BFISMA and BFIPV in group βwith IAHβ were lower by 54.38% (P < 0.01) and 63.11% (P < 0.01) respectively compared to group βwithout IAHβ. There were strong significant negative correlation between IAP and BFISMA (rs = β0.66; P < 0.0001), weak significant negative correlation between IAP and BFIPV (rs = β0.36; P = 0.0001) in group βwith IAHβ and weak significant negative correlation between IAP and BFISMA (rs = β0.30; P = 0.0047) in group βwithout IAHβ. There were no statistically significant correlations between IAP and BFIPV in group βwithout IAHβ, between BFISMA and APP in both groups and between BFIPV and APP in both groups.Conclusion:Elevated IAP significantly reduces splanchnic blood flow in children with appendicular peritonitis. BFISMA and BFIPV negatively correlate with IAP in these patients. There is no correlation between BFISMA/BFIPV and APP in children with IAH due to appendicular peritonitis.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have