Abstract

Effect of Interval Training Intensity on Gene Expression of Endothelial Progenitor Cells and Cardiac Stem Cells in Aged Rats

Highlights

  • Aging is accompanied by anatomical and physiological changes in most tissues and organs, especially the reduction of cells, tissues, and vascular levels

  • We aimed to investigate the effect of eight weeks of moderate and intense interval training on gene expression of endothelial progenitor cells and cardiac stem cells in aged rats

  • These findings can be used to improve cell therapy and cardiac rehabilitation after injury and myocardial dysfunction, especially in the elderly

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Summary

Introduction

Aging is accompanied by anatomical and physiological changes in most tissues and organs, especially the reduction of cells, tissues, and vascular levels. Endothelial progenitor cells are involved in maintaining endothelial health, preventing endothelial dysfunction, and increasing neovascularization process. Cardiac stem cells are effective in the regeneration and repair of heart tissue. Regular exercise training increases both of these cells. We aimed to investigate the effect of eight weeks of moderate and intense interval training on gene expression of endothelial progenitor cells and cardiac stem cells in aged rats

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