Effect of Inspiratory Muscles Training With Threshold Loading Device in Patients With Chronic Obstructive Pulmonary Disease

Abstract

Research Objectives To find out the changes of inspiratory muscle strength by manometer, to assess the changes of exercise tolerance by 6MWT, to assess the changes of FEV1 and FVC with the spirometer and to assess the quality of life by COPD assessment test at 0, 2nd, 4th and 6th week in patients with COPD treated with the inspiratory muscles training using threshold loading device. Design Hospital-based quasi-experimental study. Setting The study was conducted at hospitalized care. Participants Participants (N=30) were diagnosed with COPD by attending physicians, age between 40 and 80, and both male and female by convenience sampling method. Interventions The participants received inspiratory muscles training (IMT) with a threshold loading device. Main Outcome Measures The main outcome measures were (1) maximum inspiratory pressure, (2) Forced vital capacity (FVC) and Forced expiratory volume in one second (FEV1), (3) the 6-minute walk test (6-MWT), and (4) the COPD Assessment Test (CAT) questionnaire. Results The baseline maximal inspiratory pressure was 69.9 cmH2O and 16.7±5.8 cmH2O (Mean+SD) at the sixth week, and the p-value was 0.01. At the baseline assessment, FEV1 and FVC were 1.3 L and 1.8 L and 0.68±0.18 (Mean+SD) and 0.46±0.26 (Mean+SD) at the sixth week, and p-value were 0.01 and 0.007. The 6-MWT was 249 meters and 25.8±8.4 (Mean+SD) at the sixth week, and the p-value was 0.008. The CAT score was 11 before intervention and -3.9±2.2 (Mean+SD) at the sixth week, and the p-value was 0.01. Conclusions There were improvements in inspiratory pressure, lung functions, exercise tolerance, and quality of life both clinically and statistically by the IMT with the threshold loading device in this study. Therefore, inspiratory muscles training with a threshold loading device should be used as the routine treatment in patients with COPD. Author(s) Disclosures There is no conflicts and disclosures. To find out the changes of inspiratory muscle strength by manometer, to assess the changes of exercise tolerance by 6MWT, to assess the changes of FEV1 and FVC with the spirometer and to assess the quality of life by COPD assessment test at 0, 2nd, 4th and 6th week in patients with COPD treated with the inspiratory muscles training using threshold loading device. Hospital-based quasi-experimental study. The study was conducted at hospitalized care. Participants (N=30) were diagnosed with COPD by attending physicians, age between 40 and 80, and both male and female by convenience sampling method. The participants received inspiratory muscles training (IMT) with a threshold loading device. The main outcome measures were (1) maximum inspiratory pressure, (2) Forced vital capacity (FVC) and Forced expiratory volume in one second (FEV1), (3) the 6-minute walk test (6-MWT), and (4) the COPD Assessment Test (CAT) questionnaire. The baseline maximal inspiratory pressure was 69.9 cmH2O and 16.7±5.8 cmH2O (Mean+SD) at the sixth week, and the p-value was 0.01. At the baseline assessment, FEV1 and FVC were 1.3 L and 1.8 L and 0.68±0.18 (Mean+SD) and 0.46±0.26 (Mean+SD) at the sixth week, and p-value were 0.01 and 0.007. The 6-MWT was 249 meters and 25.8±8.4 (Mean+SD) at the sixth week, and the p-value was 0.008. The CAT score was 11 before intervention and -3.9±2.2 (Mean+SD) at the sixth week, and the p-value was 0.01. There were improvements in inspiratory pressure, lung functions, exercise tolerance, and quality of life both clinically and statistically by the IMT with the threshold loading device in this study. Therefore, inspiratory muscles training with a threshold loading device should be used as the routine treatment in patients with COPD.