Effect of incorporation of nano-hydroxyapatite particles on the clinical performance of conventional and resin-modified glass ionomer cement in class V cavities: split-mouth, randomized controlled trial

Dina W. Elkassas,Shaymaa M. Nagi,Maha A. Niazy,Zeinab M. Zaki,Mohamed H. Zaazou

doi:10.1186/s42269-021-00655-2

Abstract

BackgroundThe aim of this study was to compare the clinical performance of Nano-hydroxyapatite-modified conventional glass ionomer cement (NHA-GIC) and Nano-hydroxyapatite-modified resin-modified glass ionomer cement (NHA-RMGIC) with conventional glass ionomer (CGIC) and resin-modified glass ionomer (RMGIC) in the treatment of caries class V cavities. Sixty patients with at least two cervical caries lesions participated in this study. A total of 120 class V cavities were prepared and then restored using different restorative materials. Restorations were clinically evaluated according to modified United States Public Health Service criteria at baseline and after 3, 6 and 9 months.ResultsThere was no statistically significant difference in the clinical performance of the different restorative materials at any of the follow-up periods. However, throughout the study period there was a statistically significant change in the color match, surface texture and marginal integrity in NHA-GIC. A statistically significant change in the surface texture and marginal integrity was found in GIC. On the other hand, there was only a statistically significant change in surface texture in NHA-RMGIC.ConclusionsAll tested restorative materials, control (CGIC and RMGIC) as well as experimental (NHA-GIC and NHA-RMGIC), exhibited comparable clinical performance after 9 months follow-up.

Highlights

The aim of this study was to compare the clinical performance of Nano-hydroxyapatite-modified conventional glass ionomer cement (NHA-glass ionomer cements (GICs)) and Nano-hydroxyapatite-modified resin-modified glass ionomer cement (NHA-Resin-Modified Glass Ionomer Cement (RMGIC)) with conventional glass ionomer (CGIC) and resin-modified glass ionomer (RMGIC) in the treatment of caries class V cavities
Conventional glass ionomer and resin-modified glass ionomer have been advocated for restorations of class V restorations, especially in patients with high caries risk
A number of clinical trials have assessed the performance of GICs for restoring cervical lesions and these trials have demonstrated acceptable clinical results (Mahn et al 2015; Priyadarshini et al 2017)

Summary

Introduction

The aim of this study was to compare the clinical performance of Nano-hydroxyapatite-modified conventional glass ionomer cement (NHA-GIC) and Nano-hydroxyapatite-modified resin-modified glass ionomer cement (NHA-RMGIC) with conventional glass ionomer (CGIC) and resin-modified glass ionomer (RMGIC) in the treatment of caries class V cavities. A number of clinical trials have assessed the performance of GICs for restoring cervical lesions and these trials have demonstrated acceptable clinical results (Mahn et al 2015; Priyadarshini et al 2017). This might be related to the unique properties of GICs, such as chemical bonding to enamel and dentin, good sealing to cavity walls, caries-inhibition effect, remineralization potential due to the gradual release of fluoride ions for a long period, a coefficient of thermal expansion and elastic modules similar to those of the tooth structure, as well as minimal effect on the pulp tissue and easy handling properties (Singh et al 2011)

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