Abstract

CANCER is more common in transplant recipients than in the general population. The reported incidence of malignant tumors after renal transplantation is 14 to 500 times higher than the rate in the general population. The prevalence of malignant tumors in different series of renal recipients ranges from 1 to 16% (mean 4%) and varies with type of organ transplant, age of the recipient, individual transplant center, and type of immunosuppression (IS). Other possible contributing factors are chronic antigenic stimulation, oncogenic virus activation, genetic susceptibility, and uremia. In this article, we describe 50 cases of malignant tumor development in renal transplant recipients who were treated with different immunosuppressive protocols in the Transplantation Center at Baskent University Faculty of Medicine.

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