Abstract
The proliferation of blood lymphocytes from nonpregnant, nonlactating heifers was comparable with that of nonpregnant cows in their first lactation. Both low and high levels of β-hydroxybutyrate and low levels of prolactin, but not isoproterenol, reduced the proliferative response of dairy heifers and cows in their first or second lactation.
Highlights
The proliferation of blood lymphocytes from nonpregnant, nonlactating heifers was comparable with that of nonpregnant cows in their first lactation
We hypothesized that lactation number (0, 1, and 2) and the concentration of BHB, isoproterenol, and prolactin affect in vitro proliferation of peripheral blood mononuclear cells (PBMCs)
A difference in the PBMC response has been observed between primi- and multiparous cows that are in early lactation and not pregnant (Kashiwazaki et al 1985; Schulz et al 2015), in midlate lactation and pregnant (Mehrzad and Zhao 2008; Tienken et al 2015), and in late lactation and not pregnant
Summary
The proliferation of blood lymphocytes from nonpregnant, nonlactating heifers was comparable with that of nonpregnant cows in their first lactation. Both low and high levels of β-hydroxybutyrate and low levels of prolactin, but not isoproterenol, reduced the proliferative response of dairy heifers and cows in their first or second lactation.
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
