Abstract
Hypolaetin-8-glucoside, a flavonoid isolated from Sideritis mugronensis possessing anti-inflammatory activity inhibited dose-dependently the human PRP aggregation induced by ADP with a IC50 = 2.4 × 10-4 M. This action does not seem to be related to cyclo-oxygenase, as this flavonoid is not an inhibitor and even is able to act as a cofactor for this enzyme.
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