Effect of hypoglycemia induced by insulin on the depth EEG in the chicken

Abstract

Changes in the depth EEG activity resulting from hypoglycemia were demonstrated in hypnotized chickens. Hypoglycemia was induced by insulin injection. In waking birds, no distinguishable changes were clicited by hypoglycemia in the EEG activity of areas such as the surface, nucleus rotundus, anterior hypothalamus, and ektostriatum (EKT). However, in the EKT, the characteristic high-amplitude, lowfrequency EEG waves of the hypnotized chicken were replaced by low amplitude fast waves when the birds were hypoglycemic, and these low amplitude fast waves were replaced by high amplitude slow waves in hypnotized birds when plasma glucose levels were raised to the normal levels by glucose injection. The EEG of other areas studied was not affected by hypoglycemia even in the hypnotic state. These results indicate that the EKT is associated with plasma glucose changes in chickens.