Abstract
Previous studies from our laboratory showed that HSYA significantly reduced the myocardial infarct size. The aim of this study is to evaluate effect of HSYA combined with nitroglycerin on acute myocardial infarction. Fifty SD rats were randomly divided into five groups with ten rats in each group: control group (NS 1 ml/100 g), model group (NS 1 ml/100 g), HSYA group (10 mg/kg), nitroglycerin (NTG) group (0.3 mg/kg) and HSYA+NTG group (10 mg/kg+0.3 mg/kg). After the left anterior descending branch of the coronary artery ligation except the sham group the rats were administered immediately the drug by intraperitoneal injection.
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