Abstract
ConclusionThe partial hydrogenation of the alcohol-soluble fraction of lard, leading to the complete or almost complete destruction of the linoleic acid contained therein, does not diminish the effectiveness of the fat with respect to the lowering of the abnormal respiratory quotients of rats on a fat-deficient diet. Further indication is thereby given that the carbohydrate factor postulated as present in natural fats is not linoleic acid, the lack of which in the diet of rats has been found to produce other deficiency symptoms.One of us reported1 that extremely small amounts of fats have an influence on metabolism greatly in excess of their effect as fat per se because of a possible new dietary factor present in the fats. Evans and Burr2 announced the discovery of a syndrome characterized by subnormal growth and retardation or suppression of ovulation, which developed in rats maintained on a fat-deficient diet. Burr and Burr3 described additional symptoms of this fat deficiency disease in rats as scaly s...
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