Abstract
Contemporary dentistry restores missing teeth with dental implants or dentures. Dental implants, despite being the preferred treatment modality, can fail and have no ability to remodel with surrounding bone, which undergoes physiologically necessary remodelling throughout life [1].
Highlights
Contemporary dentistry restores missing teeth with dental implants or dentures
We further show therapeutic strategies focusing on the stimulation of endogenous cells to support periimplant bone repair
Some of them co-expressed markers of fibroblasts or osteoblasts. These results indicated that Neural crest-related stem cells (NCSCs) might contribute to the formation of new fibers and periimplant bone tissue during periimplant bone regeneration
Summary
Contemporary dentistry restores missing teeth with dental implants or dentures. Despite being the preferred treatment modality, can fail and have no ability to remodel with surrounding bone, which undergoes physiologically necessary remodelling throughout life [1]. There has been intensifying interest in the regeneration of orofacial tissues [2,3,4]. This increasing popularity of dental implant surgery has further created a heavy demand for dento-alveolar reconstruction. Insufficient alveolar contours may require bone grafting procedures to restore adequate bone volume before implant placement to counteract potentially harmful results, such as higher failure rates and unsatisfactory aesthetic results [5,6]. Osseointegration, crucial for the success of an implant, is influenced by several factors such as treatment indication, implant material, implant surface, implant shape, treatment planning, implant surgery, and by the quality and quantity of the bone
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