Abstract
LIF is a cytokine with an important role in early embryo development (Stewart C, 1994), and it was shown that human LIF (hLIF) is critical in maintaining the totipotentiality of embryonic stem cells (Williams R, 1988). Also, it appears to improve the development of parthenogenic bovine embryos (Fukui Y,1994) as well as previously frozen bovine embryos (Han Y,1995).
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