Abstract
The microorganism in human body is related to human health and disease, which plays a significant role in the exclusion of pathogen invading, participation of immune regulation and occurrence and development of the tumors. Studies have indicated that dysbacteriosis is often detected in cancer patients; especially, enteric dysbacteriosis can promote the occurrence and development of the tumors by influencing homeostatic balance of intestinal tract, gut metabolite and immunological function. Moreover, proportion detection of intestinal flora can be used as a non-invasive screening method and a diagnostic indicator for early detection of the malignant neoplasms. This review summarizes the recent studies on the associations of intestinal flora with human diseases and the possible mechanisms causing tumorigenesis, which may provide a novel research paradigm for cancer prevention and treatment. Key words: Neoplasms; Gut microbiota; Mechanism; Diagnosis
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