Year-end Sale % OFF 
Abstract
Human leukocyte interferon, human fibroblast interferon, mouse interferon and an interferon inducer, polyriboinosinic acid·polyribocytidylic acid (poly(I)·poly(C)), were examined for their effect on the growth of two human tumor cell lines in athymic nude mice. The human tumor cell lines were derived from a fibrosarcoma (designated HT- 1080) and a nonmelanotic melanoma (designated A- 375). Repeated doses of 5 mg/kg of poly(I)·poly(C), administered every other day starting 1 day after tumor cell inoculation, caused a significant inhibition of tumor growth. On the contrary, human (leukocyte or fibroblast) interferon and mouse interferon, at doses up to 5 × 10 6 units/kg , did not affect the growth of either of the two human tumor cell lines tested.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
