Effect of Huayu Qufu Shengji Decoction on Postoperative Pain and Wound Healing Time in Patients with Perianal Abscess

Abstract

This study aimed to investigate the impact of postoperative pain and wound healing time in patients who underwent perianal abscess surgery. A total of 106 patients who underwent perianal abscess surgery from July 2019 to May 2021 were enrolled as study subjects and randomly divided into a control group and a treatment group with 53 patients in each group. The control group received potassium permanganate sitz bath after surgery, while the treatment group received smoked Huayu Qufu Shengji decoction after surgery. The levels of postoperative pain (measured by visual analog scale score), wound healing, inflammatory factors and treatment response rate were compared between the two groups. Before treatment, the visual analog scale scores were similar in both groups (p>0.05). However, after treatment, the visual analog scale scores in both groups decreased significantly and the visual analog scale score in the treatment group was lower than that in the control group (p<0.05). Moreover, the treatment group had a shorter wound shedding time, a quicker emergence of new epithelium and a smaller wound healing time compared to the control group (p<0.05). Before treatment, the levels of inflammatory factors such as tumor necrosis factor alpha, interleukin-6 and interleukin-1 beta were similar in both groups (p>0.05). However, after treatment, the level of each inflammatory factor was lower in the treatment group than in the control group (p<0.05). The treatment group showed a significantly higher treatment response rate than the control group (p<0.05). The application of smoked Huayu Qufu Shengji decoction and sitz bath in patients who underwent perianal abscess surgery can relieve pain, promote faster wound healing and improve the inflammation state, resulting in a significant overall effect. Therefore, this treatment can be preferred as a first-line therapy.