Abstract
SummaryHistone influenced lipid transport in the same manner as protamine. In nonlipemic dogs, it failed to influence unesterified or esterified fatty acids, reversed the action of heparin on clearing activity, and opposed the elevation of unesterified fatty acids. In lipemic dogs, histone increased lipemia without affecting the unesterified fatty acids. In similar animals after heparin, histone reversed the action of heparin, increasing lipemia and decreasing clearing activity of the plasma and unesterified fatty acids.
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