Abstract
Marked elevation of serum free fatty acids (FFA) was induced by infusing triglyceride and heparin in 8 normal dogs, in 6 dogs immediately after coronary ligation, and in 8 dogs 3 days after ligation. The ventricular fibrillation threshold (VFT) was measured in closed chest dogs by delivering a programmed series of impulses directly to the heart via previously implanted epicardial electrodes. There was no change in the VFT after FFA elevation in the normal dogs. Dogs with coronary occlusion had lower control VFT. However, there was no further drop after FFA elevation. These data argue against a major direct role of FFA in genesis of ventricular fibrillation related to myocardial ischemia.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
