Abstract
Background:Type 2 diabetes (T2D) is a significant health concern worldwide, and good glycemic control is the basis of avoiding disease progression. Herbal tea, as a convenient and effective medication method, has gained popularity among many diabetic patients. However, there are no systematic reviews or meta-analyses to evaluate the clinical efficacy of herbal tea on T2D.Methods:Four English electronic databases and 4 Chinese electronic databases were searched for randomized controlled trials (RCTs) meeting inclusion criteria; Clinical trials were searched to explore the relevant unpublished data. Fasting blood glucose and glycated hemoglobin will be measured as primary outcomes. Secondary outcomes include 2-hour postprandial blood glucose, fasting insulin, and homeostasis model assessment-insulin resistance. The heterogeneity of data will be investigated by Chi-square and I2 test; subgroup analysis and sensitivity analysis will be conducted to explore the sources of heterogeneity; funnel plot will be used to evaluate publication bias; finally, we will use grading of recommendations assessment, development, and evaluate system method to evaluate the quality of evidence. Merging analysis of data will be performed using Rev Man 5.3 software.Results:The results will be published in a peer-reviewed journal.Conclusions:The systematic review will confirm whether herbal tea consumption is benefit to the glycemic control in patients with T2D.PROSPERO registration number:CRD42019129863.
Highlights
Diabetes has become a significant health concern in the past decades
This systematic review and meta-analysis protocol have been registered on the international prospective register of systematic review (PROSPERO) and the registration number is CRD42019129863
This systematic review and meta-analysis protocol is reported according to the preferred reporting items for systematic reviews and meta-analysis protocols checklist.[18]
Summary
Data from the International Diabetes Federation indicate that approximately 425 million adults (aged 20–79 years) have this disease, and US$673 billion was spent to improve. Effect of herbal tea on glycemic control in patients with type 2 diabetes: protocol for a systematic review and meta-analysis. Type 2 diabetes (T2D) is a significant health concern worldwide, and good glycemic control is the basis of avoiding disease progression. There are no systematic reviews or meta-analyses to evaluate the clinical efficacy of herbal tea on T2D
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