Abstract
Successful embryo implantation and appropriate trophoblast invasion is associated with an adequate communication and interaction between peripheral blood mononuclear cells (PBMC) and the human embryo. Human chorionic gonadotropin (hCG) is one of the earliest embryonic signals that affect PBMC cytokine secretion. Nowadays, the intrauterine administration of hCG-activated autologous PBMC is a widely used treatment for improvement of pregnancy outcome. However, the effect of hCG on PBMC cytokine secretion is scarcely studied.
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