Effect of growth hormone administration on ICSI outcomes in patients with polycystic ovary syndrome and recurrent implantation failure: A retrospective cross-over study.

Abstract

Recurrent implantation failure (RIF) may be observed in some young women with polycystic ovary syndrome (PCOS) after in-vitro fertilization (IVF) [1]. The observation that administration of growth hormone (GH) during ovarian stimulation may improve IVF outcomes, not only in women aged >40 years [2] but also in younger women with RIF [3], led us to consider the use of GH therapy in women with RIF, independently of their age.