Abstract

Effect of garden cress Lepidium sativum (a cruciferous plant) on induction of chromosomal aberrations in bone marrow cells of white mice was studied , in addition to its effect to reverse the chromosomal aberrations induced by drug cyclophosphamide (Cp). The results showed that Cp induced chromosomal aberrations in order of 4.7 folds of the natural state , i.e., Negative control (1.75) , the high level of chromosomal aberrations continued for 6 days and the difference was insignificant compared to the positive control (P

Highlights

  • The results showed that Cp induced chromosomal aberrations in order of 4.7 folds of the natural state, i.e., Negative control (1.75), the high level of chromosomal aberrations continued for 6 days and the difference was insignificant compared to the positive control (P

  • No chromosomal aberrations was induced by when used at 0.1, 0.25, 0.5 ml / animal administrated orally and the aberrations were statistically insignificant compared to the negative control

  • Chemoprotective effects of 2-amino- 3- methyl-imidazo[4,5-f] quinoline (IQ)- induced colonic and hepatic preneoplastic lesions in the F433 rat by cruciferous vegetables administrated simultaneously with carcinogen

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Summary

Introduction

‫مستوى منخفض وكذلك استعمال العصیر بعد حصول التشوھات )‪(Cp/R‬‬ ‫درست الكروموسومات في خلایا نقي العظام وفق الطرق المتبعة ) ‪ Metcalf‬واخرون ‪(١٩٨٦ ،‬‬ ‫المعاملة الاولى ‪ :‬تجریع الحیوانات بالعصیر النباتي قبل المطفر )‪ ، ‫الجرعة الثانیة للعصیر النباتي ‪ ،‬ثم تم تشریح الحیوانات في الیوم الثالث ‪.‬‬ ‫المجموعة الثالثة ‪ :‬ضمت ‪ ٣‬فئران تم تجریعھا بالعصیر النباتي لمدة ‪٦‬‬

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