Abstract
Five hundred and twenty-eight female mice were randonfly divided into twelve groups and given fractionated doses of gamma rays ranging from 240 to 1200 rads and fission neutrons ranging from 92 to 451 rads. After a repair period of 90 days, they were placed in a continuous field of gamma rays where they remained until death. The mean accumulated dose for each group was determined and correlated with the insult dose. The results of this study showed that (1) radiation-induced damage in the mouse has one component that is permanent and irreversible, (2) at least a fraction of this irreversible damage is proportional to the magnitude of the insult dose and is measurable in terms of a reduction in survival time in a continuous gamma radiation field, and (3) the fraction of permanent injury produced by fission neutrons is approximately five times as great as that produced by gamma rays. A comparison of the results of this study with other experiments of a similar nature was made. (auth)
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